Cayos Zapatilla Vacations from $755

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The Latest Cayos Zapatilla vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel San Pedro de Taboga
Central Hotel Panama Casco Viejo
Megapolis Hotel Panamá
Riande Aeropuerto Hotel & Casino
Las Clementinas
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Cayos Zapatilla Hotel Deals

Hotel Eclypse de Mar Acqua Lodge

Hotel Eclypse de Mar Acqua Lodge

3 out of 5
Bocas del Toro Bastimentos
$83 nightly
The price is $91 total per night from Nov 11 to Nov 12
$91 total
Nov 11 - Nov 12
Total with taxes and fees
9.2/10 Wonderful! (117 reviews)
"Our over the water bungalow was so clean, scenic and comfortable. The staff are amazing. Everyone was smiling, accommodating and wonderful. The food in the restaurant was delicious. Very serene and calming, and just it couldn't ask for anything more. The grounds are impeccable and beautiful in a ..."

Reviewed on Nov 7, 2026

Hotel Eclypse de Mar Acqua Lodge
Cosmic Crab Resort

Cosmic Crab Resort

3 out of 5
Carenero Island Trail Bocas del Toro Bocas del Toro
$42 nightly
The price is $47 total per night from Nov 16 to Nov 17
$47 total
Nov 16 - Nov 17
Total with taxes and fees
8/10 Very Good! (151 reviews)
"I have been traveling to Cosmic Crab for 9 years. It is one of my favorite places. The resort has a rustic Caribbean vibe with one of the best sunset views in Bocas. The pool is lovely. The restaurant has delicious food. I recommend the fresh fish dishes, burgers, and pizza. The bloody Mary's and ..."

Reviewed on Oct 31, 2026

Cosmic Crab Resort
Hotel Bocas del Toro

Hotel Bocas del Toro

3.5 out of 5
Calle Nº 2 Bocas del Toro Bocas del Toro
$92 nightly
The price is $101 total per night from Dec 10 to Dec 11
$101 total
Dec 10 - Dec 11
Total with taxes and fees
9/10 Wonderful! (205 reviews)
"Great room overlooking the water with a nice comfortable covered balcony. Right in the middle of many bars restaurants and shopping. All of the staff were super friendly!"

Reviewed on Oct 11, 2026

Hotel Bocas del Toro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Cayos Zapatilla Vacation Packages

Cayos Zapatilla Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)

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Frequently asked questions

What's included in a Cayos Zapatilla vacation package?
A Cayos Zapatilla vacation package in nearby Bocas del Toro lets you combine flights, hotel stays, and rental cars. Most hotels in Bocas del Toro offer airport shuttle service to and from Bocas del Toro International Airport (BOC), and nearly all include free breakfast.

Exactly what's included will vary by hotel and package, so it's worth reviewing the details before you confirm your booking.
How can I save money on a Cayos Zapatilla vacation package?
When you bundle, you can save up to 30%*. To save money on a Cayos Zapatilla package, consider traveling during the quieter months or be flexible with your dates to find more options. Bundling your flights and hotel together often unlocks savings compared to booking separately. *Members only. Savings vary.
Is Cayos Zapatilla better suited for a beach vacation or a cultural trip?
Cayos Zapatilla is primarily a beach destination, offering travelers pristine shores and clear waters.

A Cayos Zapatilla vacation package centers on enjoying the natural beauty of the islands, including the iconic Zapatilla Island itself. The nearby hub of Bocas del Toro is also known for its beaches and outdoor activities, making it an ideal base. You can explore stunning spots like Red Frog Beach and Starfish Beach, both easily accessible from Bocas del Toro.

The region's appeal lies in its relaxed island atmosphere, scenic views, and adventure activities.
Which airport should I use for a Cayos Zapatilla vacation?
For a Cayos Zapatilla vacation, the nearest hub, Bocas del Toro, is primarily served by Bocas del Toro (BOC-Bocas del Toro Intl.) airport.

Other airports that serve the wider region include David (DAV-Enrique Malek Intl.) and Changuinola (CHX-Captain Manuel Nino Intl.). These gateways provide additional options for reaching your Cayos Zapatilla vacation.
What are the top things to do in Cayos Zapatilla?
A Cayos Zapatilla vacation is easiest to plan from the nearby hub of Bocas del Toro, which offers access to the region's natural beauty:

Browse and book things to do in Cayos Zapatilla on Expedia.
Are there family vacation packages in Cayos Zapatilla with kid-friendly amenities?
Family vacation packages in Cayos Zapatilla, with stays in the nearby hub of Bocas del Toro, offer several hotels with amenities designed for a comfortable family trip:
  • Bluff Beach Retreat: This property, rated 9.2 out of 10 by travelers, provides family rooms, a game room, and an outdoor pool, making it a great base for families. Travelers appreciate the good breakfast offered here.
  • The Hummingbird: Rated 9.5 out of 10 by travelers, this hotel features a game room and an outdoor pool, perfect for keeping children entertained. Travelers often mention its beautiful overall setting and awesome rooms.
  • Oasis Bluff Beach: With a game room and an outdoor pool, this hotel is rated 8.9 out of 10 by travelers. Travelers frequently highlight the nice pool and attentive staff.
  • Cosmic Crab Resort: Rated 7.6 out of 10 by travelers, this resort offers family rooms and an outdoor pool. Travelers often praise its beautiful overall atmosphere and great rooms.
Are Cayos Zapatilla vacation package hotels conveniently located?
Cayos Zapatilla vacation package hotels are primarily located in the nearby hub of Bocas del Toro, offering convenient access to the area's attractions. Many properties are within easy reach of central Bocas del Toro, which serves as a base for exploring the surrounding islands and beaches.

For example, Casa Acuario, rated 9.9 out of 10 by travelers, is about a 10-minute walk from central Bocas del Toro. Bambuda Bocas Town - Hostel, rated 8.7 out of 10, and the 3.5-star Tropical Suites Hotel, rated 8.6 out of 10, are both about a 5-minute walk from the center, placing you close to local amenities.
Are there vacation package hotels in Cayos Zapatilla within walking distance of restaurants and shops?
Cayos Zapatilla vacation package hotels, primarily located in the nearby hub of Bocas del Toro, offer several options within walking distance of local restaurants and shops. The central area of Bocas del Toro provides a lively atmosphere with various dining and retail choices.

For instance, Casa Acuario, rated 9.9 out of 10 by travelers, is about a 10-minute walk from central Bocas del Toro. Both Bambuda Bocas Town - Hostel, rated 8.7 out of 10, and the 3.5-star Tropical Suites Hotel, rated 8.6 out of 10, are conveniently located about a 5-minute walk from the center, putting you steps away from the town's amenities.
Can I change or cancel my Cayos Zapatilla vacation package if my plans change?
Yes, you can cancel your vacation package via your itinerary page on Expedia or by contacting customer service. Remember that some packages are fully refundable, but the details vary based on each unique booking. A fully refundable package may depend on how far out from the travel dates you're canceling and what airline you are traveling with.
Do One Key members get extra savings when booking Cayos Zapatilla vacation packages?
Yes, members who join our free One Key™ travel rewards program can instantly unlock additional savings and save 10% or more on over 500,000 stays worldwide with Member Prices and over 1 million car rentals.
Does Expedia offer Book Now, Pay Later Cayos Zapatilla vacation packages?
Yes, with Expedia's Book Now, Pay Later option, powered by Affirm, you can spread the cost of your Cayos Zapatilla vacation over 3, 6, or 12 months. With no late payment fees or hidden costs, it's easy to secure your ideal vacation package as soon as you spot it.
How do I find last-minute vacation packages to Cayos Zapatilla?
To find last-minute vacation packages to Cayos Zapatilla, explore the last-minute deals section for the latest package offers, including flights, departing in the coming weeks. Being flexible with your travel dates and hotel preferences can help you secure the best prices.
How does free cancellation work on Cayos Zapatilla vacation packages?
Free cancellation on a Cayos Zapatilla vacation package depends on the specific hotel and rate combination you book. Many bookings allow free cancellation up to a stated deadline (often a few days before travel) where eligible. Read the cancellation terms carefully when reviewing the package, and visit Expedia help center for further details.
Is it cheaper to book a Cayos Zapatilla vacation as a package or separately?
An Expedia vacation package could land you great savings when compared to arranging flights and hotels separately. Better still, you can tailor your Cayos Zapatilla getaway to match your exact preference. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
Why should I book my Cayos Zapatilla vacation package with Expedia?
Booking your vacation package on Expedia makes it easier to get more out of your trip from the start. With a wide choice of hotels, you can compare prices, reviews and amenities all in one place, then bundle your hotel with flights which could help you save even more. Flexible booking options on selected stays also make it easier to plan with confidence.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.